Advertisement 1

Inflammaging? Reverse aging? Experts explain trending skincare terms

There's a big buzzword in health these days: Inflammaging. Here's what you should know about it.

Article content

Reviews and recommendations are unbiased and products are independently selected. Postmedia may earn an affiliate commission from purchases made through links on this page.

There are two big buzzwords in beauty these days: inflammaging and reverse aging.

“Inflammaging … refers to chronic, low-grade inflammation that contributes to the development of age-related diseases and organ damage as we get older,” explains Dr. Monica Li, clinical assistant professor, Department of Dermatology and Skin Science, University of B.C., and founder, Vancouver Skin MD clinic. “As a result, certain pro-inflammatory markers are produced and may represent a strong risk factor for various, highly prevalent diseases such as cancer, depression, dementia and cardiovascular diseases.”

Advertisement 2
Story continues below
Article content

A term first coined in a 2000 paper, according to a 2018 edition of Pathology Magazine from UBC, the effects of inflammation on the body’s overall aging process are being studied in detail by researchers worldwide.

A major frontier of interest for inflammaging is within the beauty space.?

As the skin is the largest organ of the human body, it’s often regarded as a window into what’s going on inside the body as stressors and aggressors manifest in a variety of ways on the skin’s surface.

“When our organs undergo inflammation, or there is increased inflammation due to stress, physiologic functions of our skin to repair cell damage and regenerate are blunted,” says Dr. Li. “Our skin may be more easily irritated by external aggressors, from harsh fabrics to product ingredients, and less able to restore itself from sun and environmental damage.”?

According to Dr. Li, this damage shows up on the skin as fine lines, a dull skin tone and uneven colour. More severe signs include flaking and dryness with inflammation triggering pre-existing inflammatory skin conditions such as rosacea, psoriasis and eczema.

Article content
Advertisement 3
Story continues below
Article content

“Skin-care formulations that contain ingredients to support a healthy skin barrier structure — thereby helping with its physiologic functions including retaining moisture at the skin surface and preventing external irritants and microbes from entering — can help combat inflammaging,” Dr. Li advises, noting antioxidant-containing skin care, and antioxidant rich vitamins and foods, can also be beneficial.?

A cellular examination

Inflammation is often a direct response to cell damage or other forms of harmful stimuli.

Therefore, when we talk about inflammation and its effects on physical signs of aging, it opens the discussion to another trending topic: cells.

Cell senescence, or the biological aging of cells, is causing a big buzz in health and beauty realms as researchers work to better understand aging through a biological (how old cells appear) versus chronological (actual length of life) lens.

Various lifestyle factors such as diet, activity level and stress can influence many markers of aging, but advanced, continuing research is also examining the mechanisms of aging from a more direct cellular scope. And the idea of controlling the clock, or even walking it back, on physical aging through cellular repair or reduction of damage is being referred to as ‘reverse aging’ by many insiders.

Advertisement 4
Story continues below
Article content

Defined as the reversal of the body’s natural ageing processes, the research field isn’t about stopping aging, but rather slowing it down.

“We age, and there is no turning back,” says professor David Furman, a researcher at Stanford University and expert in the field of reverse aging. “Biological aging as opposed to chronological aging, is malleable … But that doesn’t mean you’re going to go back in time. The only way to do that is by doing genetic modifications.”

Rather than stop the body’s natural aging process, the goal of reverse aging research is to delay the various processes.

“And to try to improve health span that the time you’re healthy on this planet, to expand that,” Furman says. “We call that the compression of morbidity. So, not to have any disease until the very, very late stages.”

As the research into reverse aging has advanced, so too has the understanding of the impact of individual cell function in the process.

“What led to the discovery of these aging mechanisms is technology. That comes first. We now have the ability to measure 20,000 genes, 10,000 proteins, 5,000 metabolites. The list goes on and on,” Furman says.

Advertisement 5
Story continues below
Article content

Proper cell respiration is a primary pillar of the reverse aging exploration.

Respiration happens in the mitochondria of the cells, where energy is generated. That energy is in the form of ATP (adenosine triphosphate), and it’s generated through cell respiration. That energy is used for the cell to function in its required tasks — and even survive.

“It’s a very complicated thing, but the basic token of this energy is ATP,” Furman, speaking from an event hosted by the French luxury brand Dior last fall, explained.

Furman, who is also a member of the Dior Reverse Aging Board, an international assemblage of more than 600 researchers and experts, noted that when we age, our cells’ ability to produce ATP goes down, ultimately impacting the skin’s collagen and density to contribute to the signs of aging.

Dior Capture products
Dior Capture products. Photo by Dior Beauty

Exploring importance of oxygen

A relaunch and reformulation for 2025, Dior Capture doubles down on research-led innovation examining the effects of cellular respiration on skin.

“The core topic of reverse aging is the one that we are diving into. Obviously, behind that, there are so many things,” says Bruno Bavouzet, president of LVMH research. “I think it is so exciting for the future. Not only for skin care, but for any areas …

Advertisement 6
Story continues below
Article content

“Understanding that aging mechanisms are not just one. There’s multiple interactions, everywhere.”

The advanced skin-care collection, which is a reinvention of the longtime collection Capture Totale and currently includes a serum and day cream, has evolved from 50 years of skin-care science conducted by the LVMH-owned company through its Dior Science division.

Rather than focus on providing oxygen to the skin directly, the technology focuses on the transport of oxygen from the environment to cells, as a vehicle. Too much oxygen can have an oxidative effect on the skin due to free radical damage, actually accelerating signs of aging.

“Everything, in principle, can be toxic,” Furman says. “It’s all about the amount, yes. But it’s also about the ‘how’ this particular thing is made available to the cells.”

To avoid this, Dior’s approach focuses on the transport of oxygen to skin with a new technology called OX-C (Oxygeno-Collagen) Treatment, a plant-derived biopolymer.

Dior ambassador Charlize Theron is the face of the new Dior Totale skincare collection.
Dior ambassador Charlize Theron is the face of the new Dior Totale skin-care collection. Photo by Dior Beauty

Studies conducted using the main ingredients used in the two new formulations showed a 57 per cent increase in cellular respiration and a 22 per cent acceleration of epidermal regeneration, according to the company.

Advertisement 7
Story continues below
Article content

Gleaned from research and pioneering in the field of regenerative medicine, primarily with organ transplants, the skin-care range also focuses on repairing the skin’s barrier, improving hydration and plumpness through ingredients like hyaluronic acid and lily extract.

Recommended from Editorial
  1. Francis Kurkdjian, Perfume Creation Director at Parfums Christian Dior. Handout/Dior Beauty
    Dior perfumer dives into details of new water-based fragrance
  2. Face the season head on with a few skin-care switches.
    Dermatologist-approved skin care tips to prep your skin for winter — plus, two TikTok skin-care trends that actually work

Aharris@postmedia.com

Postmedia News was a guest of Dior in California. The brand neither reviewed nor approved this article.

Article content
Comments
You must be logged in to join the discussion or read more comments.
Join the Conversation

Postmedia is committed to maintaining a lively but civil forum for discussion. Please keep comments relevant and respectful. Comments may take up to an hour to appear on the site. You will receive an email if there is a reply to your comment, an update to a thread you follow or if a user you follow comments. Visit our Community Guidelines for more information.

Latest National Stories
    universo-virtual.com
    buytrendz.net
    thisforall.net
    benchpressgains.com
    qthzb.com
    mindhunter9.com
    dwjqp1.com
    secure-signup.net
    ahaayy.com
    soxtry.com
    tressesindia.com
    puresybian.com
    krpano-chs.com
    cre8workshop.com
    hdkino.org
    peixun021.com
    qz786.com
    utahperformingartscenter.org
    maw-pr.com
    zaaksen.com
    ypxsptbfd7.com
    worldqrmconference.com
    shangyuwh.com
    eejssdfsdfdfjsd.com
    playminecraftfreeonline.com
    trekvietnamtour.com
    your-business-articles.com
    essaywritingservice10.com
    hindusamaaj.com
    joggingvideo.com
    wandercoups.com
    onlinenewsofindia.com
    worldgraphic-team.com
    bnsrz.com
    wormblaster.net
    tongchengchuyange0004.com
    internetknowing.com
    breachurch.com
    peachesnginburlesque.com
    dataarchitectoo.com
    clientfunnelformula.com
    30pps.com
    cherylroll.com
    ks2252.com
    webmanicura.com
    osostore.com
    softsmob.com
    sofietsshotel.com
    facetorch.com
    nylawyerreview.com
    apapromotions.com
    shareparelli.com
    goeaglepointe.com
    thegreenmanpubphuket.com
    karotorossian.com
    publicsensor.com
    taiwandefence.com
    epcsur.com
    odskc.com
    inzziln.info
    leaiiln.info
    cq-oa.com
    dqtianshun.com
    southstills.com
    tvtv98.com
    thewellington-hotel.com
    bccaipiao.com
    colectoresindustrialesgs.com
    shenanddcg.com
    capriartfilmfestival.com
    replicabreitlingsale.com
    thaiamarinnewtoncorner.com
    gkmcww.com
    mbnkbj.com
    andrewbrennandesign.com
    cod54.com
    luobinzhang.com
    bartoysdirect.com
    taquerialoscompadresdc.com
    aaoodln.info
    amcckln.info
    drvrnln.info
    dwabmln.info
    fcsjoln.info
    hlonxln.info
    kcmeiln.info
    kplrrln.info
    fatcatoons.com
    91guoys.com
    signupforfreehosting.com
    faithfirst.net
    zjyc28.com
    tongchengjinyeyouyue0004.com
    nhuan6.com
    oldgardensflowers.com
    lightupthefloor.com
    bahamamamas-stjohns.com
    ly2818.com
    905onthebay.com
    fonemenu.com
    notanothermovie.com
    ukrainehighclassescort.com
    meincmagazine.com
    av-5858.com
    yallerdawg.com
    donkeythemovie.com
    corporatehospitalitygroup.com
    boboyy88.com
    miteinander-lernen.com
    dannayconsulting.com
    officialtomsshoesoutletstore.com
    forsale-amoxil-amoxicillin.net
    generictadalafil-canada.net
    guitarlessonseastlondon.com
    lesliesrestaurants.com
    mattyno9.com
    nri-homeloans.com
    rtgvisas-qatar.com
    salbutamolventolinonline.net
    sportsinjuries.info
    topsedu.xyz
    xmxm7.com
    x332.xyz
    sportstrainingblog.com
    autopartspares.com
    readguy.net
    soniasegreto.com
    bobbygdavis.com
    wedsna.com
    rgkntk.com
    bkkmarketplace.com
    zxqcwx.com
    breakupprogram.com
    boxcardc.com
    unblockyoutubeindonesia.com
    fabulousbookmark.com
    beat-the.com
    guatemala-sailfishing-vacations-charters.com
    magie-marketing.com
    kingstonliteracy.com
    guitaraffinity.com
    eurelookinggoodapparel.com
    howtolosecheekfat.net
    marioncma.org
    oliviadavismusic.com
    shantelcampbellrealestate.com
    shopleborn13.com
    topindiafree.com
    v-visitors.net
    qazwsxedcokmijn.com
    parabis.net
    terriesandelin.com
    luxuryhomme.com
    studyexpanse.com
    ronoom.com
    djjky.com
    053hh.com
    originbluei.com
    baucishotel.com
    33kkn.com
    intrinsiqresearch.com
    mariaescort-kiev.com
    mymaguk.com
    sponsored4u.com
    crimsonclass.com
    bataillenavale.com
    searchtile.com
    ze-stribrnych-struh.com
    zenithalhype.com
    modalpkv.com
    bouisset-lafforgue.com
    useupload.com
    37r.net
    autoankauf-muenster.com
    bantinbongda.net
    bilgius.com
    brabustermagazine.com
    indigrow.org
    miicrosofts.net
    mysmiletravel.com
    selinasims.com
    spellcubesapp.com
    usa-faction.com
    snn01.com
    hope-kelley.com
    bancodeprofissionais.com
    zjccp99.com
    liturgycreator.com
    weedsmj.com
    majorelenco.com
    colcollect.com
    androidnews-jp.com
    hypoallergenicdogsnames.com
    dailyupdatez.com
    foodphotographyreviews.com
    cricutcom-setup.com
    chprowebdesign.com
    katyrealty-kanepa.com
    tasramar.com
    bilgipinari.org
    four-am.com
    indiarepublicday.com
    inquick-enbooks.com
    iracmpi.com
    kakaschoenen.com
    lsm99flash.com
    nana1255.com
    ngen-niagara.com
    technwzs.com
    virtualonlinecasino1345.com
    wallpapertop.net
    nova-click.com
    abeautifulcrazylife.com
    diggmobile.com
    denochemexicana.com
    eventhalfkg.com
    medcon-taiwan.com
    life-himawari.com
    myriamshomes.com
    nightmarevue.com
    allstarsru.com
    bestofthebuckeyestate.com
    bestofthefirststate.com
    bestwireless7.com
    declarationintermittent.com
    findhereall.com
    jingyou888.com
    lsm99deal.com
    lsm99galaxy.com
    moozatech.com
    nuagh.com
    patliyo.com
    philomenamagikz.net
    rckouba.net
    saturnunipessoallda.com
    tallahasseefrolics.com
    thematurehardcore.net
    totalenvironment-inthatquietearth.com
    velislavakaymakanova.com
    vermontenergetic.com
    sizam-design.com
    kakakpintar.com
    begorgeouslady.com
    1800birks4u.com
    2wheelstogo.com
    6strip4you.com
    bigdata-world.net
    emailandco.net
    gacapal.com
    jharpost.com
    krishnaastro.com
    lsm99credit.com
    mascalzonicampani.com
    sitemapxml.org
    thecityslums.net
    topagh.com
    flairnetwebdesign.com
    bangkaeair.com
    beneventocoupon.com
    noternet.org
    oqtive.com
    smilebrightrx.com
    decollage-etiquette.com
    1millionbestdownloads.com
    7658.info
    bidbass.com
    devlopworldtech.com
    digitalmarketingrajkot.com
    fluginfo.net
    naqlafshk.com
    passion-decouverte.com
    playsirius.com
    spacceleratorintl.com
    stikyballs.com
    top10way.com
    yokidsyogurt.com
    zszyhl.com
    16firthcrescent.com
    abogadolaboralistamd.com
    apk2wap.com
    aromacremeria.com
    banparacard.com
    bosmanraws.com
    businessproviderblog.com
    caltonosa.com
    calvaryrevivalchurch.org
    chastenedsoulwithabrokenheart.com
    cheminotsgardcevennes.com
    cooksspot.com
    cqxzpt.com
    deesywig.com
    deltacartoonmaps.com
    despixelsetdeshommes.com
    duocoracaobrasileiro.com
    fareshopbd.com
    goodpainspills.com
    kobisitecdn.com
    makaigoods.com
    mgs1454.com
    piccadillyresidences.com
    radiolaondafresca.com
    rubendorf.com
    searchengineimprov.com
    sellmyhrvahome.com
    shugahouseessentials.com
    sonihullquad.com
    subtractkilos.com
    valeriekelmansky.com
    vipasdigitalmarketing.com
    voolivrerj.com
    zeelonggroup.com
    1015southrockhill.com
    10x10b.com
    111-online-casinos.com
    191cb.com
    3665arpentunitd.com
    aitesonics.com
    bag-shokunin.com
    brightotech.com
    communication-digitale-services.com
    covoakland.org
    dariaprimapack.com
    freefortniteaccountss.com
    gatebizglobal.com
    global1entertainmentnews.com
    greatytene.com
    hiroshiwakita.com
    iktodaypk.com
    jahatsakong.com
    meadowbrookgolfgroup.com
    newsbharati.net
    platinumstudiosdesign.com
    slotxogamesplay.com
    strikestaruk.com
    trucosdefortnite.com
    ufabetrune.com
    weddedtowhitmore.com
    12940brycecanyonunitb.com
    1311dietrichoaks.com
    2monarchtraceunit303.com
    601legendhill.com
    850elaine.com
    adieusolasomade.com
    andora-ke.com
    bestslotxogames.com
    cannagomcallen.com
    endlesslyhot.com
    iestpjva.com
    ouqprint.com
    pwmaplefest.com
    qtylmr.com
    rb88betting.com
    buscadogues.com
    1007macfm.com
    born-wild.com
    growthinvests.com
    promocode-casino.com
    proyectogalgoargentina.com
    wbthompson-art.com
    whitemountainwheels.com
    7thavehvl.com
    developmethis.com
    funkydogbowties.com
    travelodgegrandjunction.com
    gao-town.com
    globalmarketsuite.com
    blogshippo.com
    hdbka.com
    proboards67.com
    outletonline-michaelkors.com
    kalkis-research.com
    thuthuatit.net
    buckcash.com
    hollistercanada.com
    docterror.com
    asadart.com
    vmayke.org
    erwincomputers.com
    dirimart.org
    okkii.com
    loteriasdecehegin.com
    mountanalog.com
    healingtaobritain.com
    ttxmonitor.com
    bamthemes.com
    nwordpress.com
    11bolabonanza.com
    avgo.top